
副研究員(項(xiàng)目研究員)
2011年獲四川大學(xué)博士學(xué)位,2011-2012年江蘇大學(xué)材料學(xué)院助理研究員,2012-2016年美國(guó)伊利諾伊理工大學(xué)化學(xué)系博士后,2017年美國(guó)俄亥俄州立大學(xué)藥學(xué)院博士后。2018年通過(guò)中國(guó)科學(xué)院率先行動(dòng)高層次青年人才引進(jìn)計(jì)劃,加入中國(guó)科學(xué)院重慶研究院,任中國(guó)科學(xué)院大學(xué)研究生導(dǎo)師,肝膽胰疾病智慧診療工程重慶市重點(diǎn)實(shí)驗(yàn)室學(xué)術(shù)帶頭人。2019年入選(首批)重慶英才 青年拔尖人才、2022年當(dāng)選第7屆重慶市北碚區(qū)“十大杰出青年”、2023年當(dāng)選“重慶青年科技創(chuàng)新先鋒人物”。近年主要從事納米孔單分子傳感技術(shù)與方法,聚焦生物分子檢測(cè)以及生物化學(xué)反應(yīng)與生物物理過(guò)程的精確測(cè)量。目前,圍繞研究方向已獲批主持多項(xiàng)國(guó)家級(jí)和省部級(jí)項(xiàng)目,包括:中國(guó)科學(xué)院率先行動(dòng)“百人計(jì)劃”人才培育項(xiàng)目、國(guó)家自然科學(xué)基金項(xiàng)目、科技部國(guó)家重點(diǎn)研發(fā)計(jì)劃子課題、重慶市自然科學(xué)基金和創(chuàng)新創(chuàng)業(yè)支持計(jì)劃等項(xiàng)目;在Small Methods 、Biosensors Bioelectronics 、 Trends in Analytical Chemistry 、ACS Sensors、 Analytical Chemistry等國(guó)際期刊發(fā)表論文40余篇,申請(qǐng)發(fā)明專利10余項(xiàng),授權(quán)5項(xiàng)。
生物醫(yī)藥與健康研究所
單分子生物傳感技術(shù)
2019年,重慶英才 青年拔尖人才
2022年,第七屆重慶市北碚區(qū)“十大杰出青年”
2023年,“重慶青年科技創(chuàng)新先鋒人物”
1.Xiaohan Chen, Shuo Zhou, Yunjiao Wang, Ling Zheng, Sarah Guan, Deqiang Wang, Liang Wang* and Xiyun Guan*. Nanopore single-molecule analysis of biomarkers: Providing possible clues to disease diagnosis. Trends in Analytical Chemistry. 2023. 162. 117060. (IF14.91)
2.Shaoxia Zhang, Yunjiao Wang, Dandan Song, Sarah Guan, Daming Zhou, Linyu Gong, Liyuan Liang, Xiyun Guan* and Liang Wang*. Nanopore discrimination and sensitive plasma detection of multiple natriuretic peptides: The representative biomarker of human heart failure. Biosensors Bioelectronics. 2023. 231. 115299. (IF12.6)
3.Dandan Song, Yunjiao Wang, Shaoxia Zhang, Lingyu Zhao, Linyu Gong, Liyuan Liang and Liang Wang*. Single-molecule Measurement of Carbonic Anhydrase in Cation Coordinated Environment Using MspA Nanopore. Chinese Journal of Chemistry. 2023. 41. 1341-1347. (cover story)
4. Minghan Li, Shanchuan Chen, Yunjiao Wang, Shaoxia Zhang, Dandan Song, Rong Tian, Jia Geng, Liang Wang.* Label-free high-precise nanopore detection of endopeptidase activity of anthrax lethal factor regulated by diverse conditions. Biosensors Bioelectronics. 2023. 219. 114800. (IF12.6)
5.Wei Li, Yunjiao Wang, Yicen Xiao, Minghan Li, Qianshan Liu, Liyuan Liang, Wanyi Xie, Deqiang Wang*, Xiyun Guan*, and Liang Wang*. Simultaneous Dual-Site Identification of 5mC/8oG in DNA Triplex Using a Nanopore Sensor. ACS Applied Materials Interfaces. 2022. 14. 32948. (IF 10.38, cover story)
6.Liang Wang, Han Wang, Xiaohan Chen, Shuo Zhou, Yunjiao Wang, * and Xiyun Guan*. Chemistry solutions to facilitate nanopore detection and analysis. Biosensors Bioelectronics. 2022. 213. 114448. (IF12.6)
7.Yicen Xiao, Juansheng Ren, Yunjiao Wang, Xiaohan Chen, Shuo Zhou, Minghan Li, Fangyuan Gao, Liyuan Liang, Deqiang Wang, Guangjun Ren* and Liang Wang *. De novo Profiling of Insect-resistant Proteins of Rice via Nanopore Peptide Differentiation. Biosensors Bioelectronics. 2022. 212. 114415. (IF12.6)
8.Han Wang, Wenli Huang, Yunjiao Wang, Wei Li, qianshan liu, Bohua Yin, Liyuan Liang, Deqiang Wang, Xiyun Guan*, Liang Wang*. Enzyme hinders HIV-1 Tat viral transport and real-time measured with nanopores. ACS Sensors. 2021. 6. 3781. (IF 9.6, cover invitation)
9.Golbarg Mohammadi Roozbahani, Xiaohan Chen, Youwen Zhang, Liang Wang* and Xiyun Guan*. Nanopore Detection of Metal Ions: Current Status and Future Directions. Small Methods. 2020. 4. 2000266. (IF15.1)
1.水稻抗褐飛虱基因編碼SCR蛋白在跨膜通道中遷移的研究。國(guó)家自然科學(xué)基金項(xiàng)目 2019-2021。主持
2.基于納米孔技術(shù)的生物分子單分子檢測(cè)研究。中國(guó)科學(xué)院青年人才項(xiàng)目 2018-2020。主持
3.重慶英才 青年拔尖人才。2019-2022。 主持
4.水稻抗褐飛虱基因編碼SCR蛋白的納米孔研究。重慶自然科學(xué)基金。2018-2021。主持